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. 2013 Mar 6:2:1.
doi: 10.4103/2277-9175.107959. Print 2013.

The influence of ureteral orifice configuration on the success rate of endoscopic treatment of vesicoureteral reflux

Affiliations

The influence of ureteral orifice configuration on the success rate of endoscopic treatment of vesicoureteral reflux

Farshid Alizadeh et al. Adv Biomed Res. .

Abstract

Background: To investigate the effect of polyacrylate polyalcohol copolymer (Vantris) injection for the correction of VUR in children according to ureteral orifice shape and VUR grade.

Materials and methods: Forty children (29 girls and 11 boys) with 61 renal refluxing units (RRU) and primary VUR underwent endoscopic correction of their reflux, using Vantris. Under general anesthesia, routine cystoscopy was performed and ureteral orifice configuration and dynamic hydro distention grade were determined. The injection technique was STING, HIT or a combination of them. Ultrasound scan was performed one and 3 months after injection and radionuclide cystography (RNC) was performed 3 months after the operation.

Results: The mean volume of injected Vantris was 0.62 cc. Reflux was corrected in 52 (85.2%) of the 61 RRU after single injection and this equates reflux correction in 37 of the 40 patients. No significant correlation was observed between ureteral orifice shape and VUR correction rate.

Conclusions: Our results showed that there was no correlation between the ureteral orifice configuration and the success rate of endoscopic surgery for VUR in short term.

Keywords: Endoscopic; polyacrylate polyalcohol copolymer; ureteral orifice; vesicoureteral reflux.

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Conflict of interest statement

Conflict of Interest: None declared

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References

    1. Chertin B, Arafeh WA, Zeldin A, Kocherov S. Preliminary data on endoscopic treatment of vesicoureteric reflux with polyacrylate polyalcohol copolymer (Vantris®): Surgical outcome following single injection. J Pediatr Urol. 2011;7:654–7. - PubMed
    1. Molitierno J, Scherz H, Kirsch A. Endoscopic treatment of vesicoureteral reflux using dextranomer hyaluronic acid copolymer. J Pediatr Urol. 2008;4:221. Epub 2008 Mar 5. - PubMed
    1. Ormaechea M, Ruiz E, Denes E, Gimenez F, Dénes FT, Moldes J, et al. New tissue bulking agent (polyacrylate polyalcohol) for treating vesicoureteral reflux: Preliminary results in children. J Urol. 2010;183:714–7. - PubMed
    1. Yücel S, Tarcan T, Sim ek F. Durability of a single successful endoscopic polytetrafluoroethylene injection for primary vesicoureteral reflux: 14-year follow-up results. J Urol. 2007;178:265–8. - PubMed
    1. Kajbafzadeh AM, Habibi Z, Tajik P. Endoscopic subureteral urocol injection for the treatment of vesicoureteral reflux. J Urol. 2006;175:1480–3. - PubMed