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Case Reports
. 2013 Mar 6:2:6.
doi: 10.4103/2277-9175.107969. Print 2013.

An insight into genetics of non-syndromic cleft palate

Nayereh Nouri  1 , Padideh Karimi, Salehi Mansoor, Mehrdad Memarzadeh, Hamid Ganji, Maryam Sedghi
Affiliations
Case Reports

An insight into genetics of non-syndromic cleft palate

Nayereh Nouri et al. Adv Biomed Res. .

Abstract

Our proband is a 29-year-old man, who is affected with soft cleft palate and hypernasality. A study of about six generations of this family pedigree shows that cleft palate has repeatedly occurred in males, with probably a X-linked recessive pattern of inheritance. Interestingly, the sister of the proband is affected with hypernasality and she has an affected son. This is the first report of X-linked inheritance pattern of cleft palate in Iran.

Keywords: Cleft palate; X-linked; inheritance pattern.

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Conflict of interest statement

Conflict of Interest: None declared

Figures

Figure 1
Figure 1
Six generations of pedigree with X-linked soft cleft palate
See this image and copyright information in PMC

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