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. 2012 Jul;16(3):283-5.

Idiopathic acute transverse myelitis: Complete recovery after intravenous immunoglobulin

E Pavlou  1 , A Gkampeta, K Kouskouras, A Evangeliou, F Athanasiadou-Piperopoulou
Affiliations

Idiopathic acute transverse myelitis: Complete recovery after intravenous immunoglobulin

E Pavlou et al. Hippokratia. 2012 Jul.

Abstract

Idiopathic acute transverse myelitis is a focal inflammatory disorder of the spinal cord of unknown etiology diagnosed according to established criteria. As it occurs rarely in children herein we report a case of a 4 year old boy who developed clinical and radiological manifestations of myelitis, 10 days after a recent respiratory tract infection. Diagnostic workup failed to reveal a causative factor. After the administration of corticosteroids a clinical deterioration was observed and intravenous immunoglobulin was administered. Symptoms resolved within a 48-hour period, suggesting an immune-mediated pathogenetic mechanism.

Keywords: acute transverse myelitis; children; idiopathic; intravenous immunoglobulin.

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Figures

Figure 1
Figure 1. Spinal magnetic resonance imaging (MRI) exhibiting high T2 signal and swelling extending from A2 to A5.
Figure 2
Figure 2. New spinal MRI scan four weeks later showing complete resolution of the lesion.
See this image and copyright information in PMC

References

    1. de Seze J, Stojkovic T, Breteau G, Lucas C, Michon-Pasturel U, Gauvrit JY, et al. Acute myelopathies :clinical, laboratory and outcome profiles in 79 cases. Brain. 2001;124:1509–1521. - PubMed
    1. Krishnan C, Kaplin AI, Deshpande DM, Pardo CA, Kerr DA. Transverse myelitis: pathogenesis, diagnosis and treatment. Front Biosci. 2004;9:1483–1499. - PubMed
    1. Proposed diagnostic criteria and nosology of acute transverse myelitis. Transverse Myelitis Consortium group. 2002;59:499–505. - PubMed
    1. de Seze J, Lanctin C, Lebrun C, Malikova I, Papeix C, Wiertlewski S, et al. Idiopathic acute transverse myelitis : Application of the recent diagnostic criteria. Neurology. 2005;65:1950–1953. - PubMed
    1. Scotti G, Gerevini S. Diagnosis and differential diagnosis of acute transverse myelopathy. The role of neuroradiological investigations and review of the literature. Neurolo Sci. 2001;22 Suppl 2:s69–s73. - PubMed

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