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Randomized Controlled Trial
. 2013 Aug 2;8(8):e68319.
doi: 10.1371/journal.pone.0068319. Print 2013.

Higher gravidity and parity are associated with increased prevalence of metabolic syndrome among rural Bangladeshi women

Shamima Akter  1 , Subrina Jesmin, Md Mizanur Rahman, Md Majedul Islam, Most Tanzila Khatun, Naoto Yamaguchi, Hidechika Akashi, Taro Mizutani
Affiliations
Randomized Controlled Trial

Higher gravidity and parity are associated with increased prevalence of metabolic syndrome among rural Bangladeshi women

Shamima Akter et al. PLoS One. .

Abstract

Background: Parity increases the risk for coronary heart disease; however, its association with metabolic syndrome among women in low-income countries is still unknown.

Objective: This study investigates the association between parity or gravidity and metabolic syndrome in rural Bangladeshi women.

Methods: A cross-sectional study was conducted in 1,219 women aged 15-75 years from rural Bangladesh. Metabolic syndrome was defined according to the standard NCEP-ATP III criteria. Logistic regression was used to estimate the association between parity and gravidity and metabolic syndrome, with adjustment of potential confounding variables.

Results: Subjects with the highest gravidity (> = 4) had 1.66 times higher odds of having metabolic syndrome compared to those in the lowest gravidity (0-1) (P trend = 0.02). A similar association was found between parity and metabolic syndrome (P(trend) = 0.04), i.e., subjects in the highest parity (> = 4) had 1.65 times higher odds of having metabolic syndrome compared to those in the lowest parity (0-1). This positive association of parity and gravidity with metabolic syndrome was confined to pre-menopausal women (P(trend) <0.01). Among the components of metabolic syndrome only high blood pressure showed positive association with parity and gravidity (P(trend) = 0.01 and <0.001). Neither Parity nor gravidity was appreciably associated with other components of metabolic syndrome.

Conclusions: Multi parity or gravidity may be a risk factor for metabolic syndrome.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

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