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. 2013 Spring;18(2):166-8.

Effectiveness of a new inflatable balloon device for gluing dissected layers in an experimental model of aortic dissection

Necmettin Colak  1 , Yunus Nazli, Mehmet Fatih Alpay, Ismail Olgun Akkaya, Omer Nuri Aksoy, Sukran Akgedik, Omer Cakir
Affiliations

Effectiveness of a new inflatable balloon device for gluing dissected layers in an experimental model of aortic dissection

Necmettin Colak et al. Exp Clin Cardiol. 2013 Spring.

Abstract

Objectives: In the surgical treatment of acute aortic dissection, tissue glues are widely used to reinforce the adhesion between the dissected aortic layers. A new inflatable balloon device was developed to compress the dissected aortic wall during gluing to increase adhesion between the dissected layers. The present study used an ex vivo experimental animal model to test the hypothesis that this device is effective when gluing the true and false channels of dissected aortas.

Methods: In the ex vivo experimental model, aortic dissection was simulated surgically on 12 fresh bovine aorta samples. In six samples (group I), the inflatable balloon device was inserted into the aorta to reinforce and fuse the dissected layers during gluing. The other six fresh bovine aortic samples (group II) were compressed between the surgeon's fingers during gluing. Aortic samples were evaluated and compared macroscopically and histologically.

Results: In group I, adhesion between the dissected layers was easily achieved during gluing. All false cavities were perfectly closed, with no deleterious effects related to the device. In group II, the adhesion between the dissected layers was not complete and some false cavities remained patent.

Conclusions: The inflatable balloon device can increase the adhesive effect of tissue glues via homogenous compression of the dissected aortic layers. In addition, the balloon can prevent distal embolization of the glue.

Keywords: Aortic dissection; New inflatable balloon device; Tissue gluing.

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Figures

Figure 1)
Figure 1)
A The balloon was inflated to a pressure of approximately 90 mmHg. B Balloon placement and application of glue in the dissected aorta. C Inflation of the balloon to a pressure of approximately 90 mmHg in the aorta. D A technical drawing of the device
Figure 2)
Figure 2)
A In all aorta samples in group I (device group), the false channels were entirely closed by glue and dissection was scarcely observed between the layers (arrow). B In group II (the control group), the dissected areas were assessed with macroscopic observation (arrow)
Figure 3)
Figure 3)
A In group I (device group), microscopic examination showed homogeneous and compact distribution of glue. Accumulation of excess glue was observed in a regular line within the layers. B In group II (the control group), irregular distribution of glue and wider dissected areas were observed between the layers
See this image and copyright information in PMC

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