Oxidative stress: Predictive marker for coronary artery disease
- PMID: 23940453
- PMCID: PMC3718605
Oxidative stress: Predictive marker for coronary artery disease
Abstract
The role of oxidative stress in cardiovascular disease processes, such as atherogenesis, ischemic-reperfusion injury and cardiac remodelling, has been increasingly recognized in the past few decades. Currently, an increasing number of studies suggest that levels of oxidative stress markers in body fluids correlate with atherosclerotic disease activity. This finding may lead to novel clinical approaches in patients with coronary artery disease. Assessment of oxidative stress markers could modify risk stratification and treatment of patients with suspected coronary artery disease or myocardial infarction.
Keywords: Myocardial infarction; Myocardial remodelling; Oxidative stress; Reactive oxygen species; Reperfusion injury.
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References
-
- Kunsch C, Medford RM. Oxidative stress as a regulator of gene expression in the vasculature. Circ Res. 1999;85:753–66. - PubMed
-
- Misra MK, Sarwat M, Bhakuni P, et al. Oxidative stress and ischemic myocardial syndromes. Med Sci Monit. 2009;15:RA209–19. - PubMed
-
- Duilio C, Ambrosio G, Kuppusamy P, et al. Neutrophils are primary source of O2 radicals during reperfusion after prolonged myocardial ischemia. Am J Physiol Heart Circ Physiol. 2001;280:H2649–57. - PubMed
-
- Kevin LG, Novalija E, Stowe DF. Reactive oxygen species as mediators of cardiac injury and protection: The relevance to anesthesia practice. Anesth Analg. 2005;101:1275–87. - PubMed
-
- Zweier JL, Talukder MA. The role of oxidants and free radicals in reperfusion injury. Cardiovasc Res. 2006;70:181–90. - PubMed
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