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. 2013 Aug 5;8(8):e70673.
doi: 10.1371/journal.pone.0070673. Print 2013.

Anterior segment optical coherence tomography for the quantitative evaluation of the anterior segment following Boston keratoprosthesis

Joann J Kang  1 , Norma Allemann, Thasarat S Vajaranant, Thasarat Vajaranant, Jose de la Cruz, Maria Soledad Cortina
Affiliations

Anterior segment optical coherence tomography for the quantitative evaluation of the anterior segment following Boston keratoprosthesis

Joann J Kang et al. PLoS One. .

Erratum in

Abstract

Objective: To quantitatively evaluate the anterior segment using anterior segment optical coherence tomography (AS-OCT) following Boston keratoprosthesis type 1.

Methods: A retrospective study consisted of AS-OCT imaging at a single time point postoperatively in 52 eyes. Main outcomes measures include anatomical and functional anterior chamber depth (ACD), angle (ACA) and peripheral and proximal synechiae.

Results: The mean time point of imaging was 19.3 months postoperatively. Average anatomical and functional ACD was 2.0 and 0.21 mm respectively, and mean ACA ranged from 2.5° to 6.14° in representative meridians. An average of 8.7 clock hours of angle closure was observed in the 25 eyes in which all meridians were imaged. The majority of eyes showed peripheral (86.5%) and proximal (67.3%) synechiae.

Conclusions: AS-OCT is a useful tool for quantitative evaluation of anterior segment and angle after keratoprosthesis, which is otherwise poorly visible. The majority of eyes showed shallow ACD, extensive angle closure and synechiae formation.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Boston keratoprosthesis and open and closed angles on AS-OCT imaging.
A, Slit-lamp photograph of implanted secondary KPro for multiple graft failure. Note that details of iris behavior and angle cannot be visualized clinically. B, Horizontal AS-OCT of the same eye with irido-corneal adhesion and closed angle. C, Slit-lamp photo of another eye with implanted primary KPro for gelatinous drop like dystrophy. Note again that details of the angle cannot be visualized and appears clinically identical to eye in part A. D, Horizontal AS-OCT of eye in part C with open angle. CO = donor cornea.
Figure 2
Figure 2. AS-OCT of implanted Boston keratoprosthesis with proximal and peripheral synechiae.
Oblique AS-OCT image with iris-backplate touch, peripheral anterior synechiae and closed anterior chamber angle. CO = donor graft; PCIOL = posterior chamber intraocular lens; PAS = peripheral anterior synechiae.
See this image and copyright information in PMC

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