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. 2013 Oct;176(3-4):295-7.
doi: 10.1007/s11046-013-9670-z. Epub 2013 Aug 13.

Reproducibility of positive results for the detection of serum galactomannan by Platelia™ aspergillus EIA

Kelly C M C Pedroza  1 , Sócrates B de Matos, Daniel L de Moura, Mônica B B Oliveira, Marco A S Araújo, Roberto J M Nascimento, Fernanda W M Lima
Affiliations

Reproducibility of positive results for the detection of serum galactomannan by Platelia™ aspergillus EIA

Kelly C M C Pedroza et al. Mycopathologia. 2013 Oct.

Abstract

Galactomannan (GM) was recently included in consensus guidelines as an indirect mycological criterion for the diagnosis of invasive aspergillosis. Currently, there is an enzyme immunoassay available to detect GM in biological samples, the Platelia™ Aspergillus EIA. In this study, the reproducibility of positive results obtained using this assay was evaluated using serum samples from neutropenic patients. A trend toward lower values was observed, and 55 %(27/49) of positive results were negative after retesting. A low reproducibility of positive results for the detection of GM in serum was observed.

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