Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Jun;5(Suppl 1):S89-94.
doi: 10.4103/0975-7406.113304.

Application of ozone in the treatment of periodontal disease

Affiliations

Application of ozone in the treatment of periodontal disease

Adusumilli Srikanth et al. J Pharm Bioallied Sci. 2013 Jun.

Abstract

Gingivitis and periodontitis are most common inflammatory diseases of supporting tissues of teeth. Role of microbial etiology and host response in progression of gingival and periodontal diseases has been well established. Because of the beneficial biological effects of ozone, due to its antimicrobial and immunostimulating effect, it is well indicated in the treatment of gingival and periodontal diseases. The objective of this article is to provide a general review about clinical applications of ozone in treatment of periodontal diseases and to summarize the available in vitro and in vivo studies in Periodontics in which ozone has been used.

Keywords: Anti-hypoxic; immunostimulating; oxidizer.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None declared.

References

    1. Grootveld M, Baysan A, Siddiqui N, Sim J, Silwood C, Lynch E. History of clinical publications of ozone. In: Lynch E, editor. Ozone: the revolution in dentistry. London: Quintessence Publishing Co; 2004. pp. 23–30.
    1. Stopka P. Ozon. Progresdent. 2003;6:8–11.
    1. Filippia A. The effect of ozonated water on epithelial wound healing. Douch Dent J. 2001;143:96–101.
    1. Sunnan GV. Ozone in medicine: Overview and future directions. J Adv Med. 1988;1:159–74.
    1. Holmes J. Clinical reversal of root caries using ozone, double-blind, randomised, controlled 18-month trial. Gerodontology. 2003;20:106–14. - PubMed