A practical guide to the monitoring and management of the complications of systemic corticosteroid therapy
- PMID: 23947590
- PMCID: PMC3765115
- DOI: 10.1186/1710-1492-9-30
A practical guide to the monitoring and management of the complications of systemic corticosteroid therapy
Abstract
Systemic corticosteroids play an integral role in the management of many inflammatory and immunologic conditions, but these agents are also associated with serious risks. Osteoporosis, adrenal suppression, hyperglycemia, dyslipidemia, cardiovascular disease, Cushing's syndrome, psychiatric disturbances and immunosuppression are among the more serious side effects noted with systemic corticosteroid therapy, particularly when used at high doses for prolonged periods. This comprehensive article reviews these adverse events and provides practical recommendations for their prevention and management based on both current literature and the clinical experience of the authors.
References
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- National Institute for Health and Clinical Excellence (NICE) Clinical Knowledge Summaries: Corticosteroids - Oral. NICE; 2012. [ http://www.cks.nhs.uk/corticosteroids_oral], Accessed February 20, 2013.
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- Singh N, Rieder MJ, Tucker MJ. Mechanisms of glucocorticoid-mediated antiinflammatory and immunosuppressive action. Paed Perinatal Drug Ther. 2004;6:107–115.
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