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Case Reports
. 2014 Mar;81(2):175-7.
doi: 10.1016/j.jbspin.2013.06.013. Epub 2013 Aug 13.

Successful treatment of Erdheim-Chester disease by interleukin-1 receptor antagonist protein

Audrey Courcoul  1 , Emmanuelle Vignot  1 , Roland Chapurlat  2
Affiliations
Case Reports

Successful treatment of Erdheim-Chester disease by interleukin-1 receptor antagonist protein

Audrey Courcoul et al. Joint Bone Spine. 2014 Mar.

Abstract

Erdheim-Chester disease is a rare non-langerhans systemic histiocytosis of unknown origin, associated with bone diseases and severe visceral complications. Therapies have been disappointing. A recombinant form of interleukin-1 receptor antagonist (anakinra) has been used in a few cases when usual treatment fails. We report a new case of successfully interleukin-1 receptor antagonist treatment in Erdheim-Chester disease.

Keywords: Anakinra; Erdheim-Chester disease; Histiocytosis; Interleukin-1 receptor antagonist protein.

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