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Comment
. 2013 Oct;9(10):603-5.
doi: 10.1038/nchembio.1322. Epub 2013 Aug 18.

Metalloenzymes: Cutting out the middleman

Souvik Roy  1 , Anne K Jones
Affiliations
Comment

Metalloenzymes: Cutting out the middleman

Souvik Roy et al. Nat Chem Biol. 2013 Oct.

Abstract

In vivo, hydrogenases require maturases for active site incorporation. However, in vitro, an active site model with limited catalytic activity could be incorporated into the apo form of [FeFe]-hydrogenase without the aid of maturases, generating enzyme with native activity.

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References

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