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. 2013:1066:169-84.
doi: 10.1007/978-1-62703-604-7_15.

Generation and analysis of biosensors to measure mechanical forces within cells

Katharina Austen  1 , Carleen Kluger, Andrea Freikamp, Anna Chrostek-Grashoff, Carsten Grashoff
Affiliations

Generation and analysis of biosensors to measure mechanical forces within cells

Katharina Austen et al. Methods Mol Biol. 2013.

Abstract

The inability to measure mechanical forces within cells has been limiting our understanding of how mechanical information is processed on the molecular level. In this chapter, we describe a method that allows the analysis of force propagation across distinct proteins within living cells using Förster resonance energy transfer (FRET)-based biosensors.

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