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Case Reports
. 2013 Apr;16(2):264-5.
doi: 10.4103/0972-2327.112490.

Vogt-Koyanagi-Harada syndrome presenting with encephalopathy

Alireza E Naeini  1 , Dana Daneshmand, Farzin Khorvash, Ahmad Chitsaz
Affiliations
Case Reports

Vogt-Koyanagi-Harada syndrome presenting with encephalopathy

Alireza E Naeini et al. Ann Indian Acad Neurol. 2013 Apr.

Abstract

VogtKoyanagi-Harada (VKH) is a rare syndrome affecting tissues with melanocytes. The possibility that VKH syndrome has an autoimmune pathogenesis is supported by the high frequency of human leukocyte antigen-DR4 commonly associated with other autoimmune diseases. Eyes are the main affected organ, resulting in blindness. Brain disease as a late onset event is extremely rare. Here, we are reporting a 57-year-old woman with previously diagnosed VKH syndrome, presenting with a late-onset brain encephalopathy. She was treated with corticosteroids and discharged from hospital with good general condition.

Keywords: Autoimmunity; Vogt-Koyanagi-Harada syndrome; encephalopathy; human leukocyte antigen (HLA).

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Conflict of interest statement

Conflict of Interest: Nil.

Figures

Figure 1
Figure 1
MRI showing diffuse T2 and FLAIR hyperintensity in the right temporal, both frontal and right parietal lobes that were hypointense in T1 weighted images
See this image and copyright information in PMC

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