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. 2012 Jan;24(1):47-50.
doi: 10.1016/j.jsha.2011.10.002. Epub 2011 Oct 24.

Angiotensin converting enzyme inhibitor as an additive treatment after successful balloon dilation of a critical pulmonary valve stenosis

M O Galal  1 , A M Alzahrani, M E Elhoury
Affiliations

Angiotensin converting enzyme inhibitor as an additive treatment after successful balloon dilation of a critical pulmonary valve stenosis

M O Galal et al. J Saudi Heart Assoc. 2012 Jan.

Abstract

A 2 days old, 2.7 kg heavy baby boy with critical pulmonary stenosis, underwent successful balloon dilation. After the uneventful procedure, he remained oxygen dependent. The baby was given oral angiotensin converting enzyme inhibitor (ACE inhibitor), instead of an infusion of alpha blocker. Within few hours, in the afternoon of the same day after administration of ACE Inhibitor, the baby could be weaned off oxygen, maintaining on room air, oxygen saturation between 87% and 92%. At follow-up, two months later, his saturation was 99% on room air. We believe that some neonates with critical pulmonary valve stenosis who remain oxygen dependent despite successful balloon dilation, could benefit from such management.

Keywords: ACE inhibitor; Alpha blocker; Critical pulmonary valve stenosis.

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Figures

Figure 1
Figure 1
The dramatic improvement of the oxygen saturation and concomitantly the rapid weaning of oxygen from 30% to room air, few hours after starting ACE inhibitor.
See this image and copyright information in PMC

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