Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Jul;19(3):129-41.
doi: 10.1016/j.jsps.2011.04.001. Epub 2011 Apr 21.

Nanoparticles: Emerging carriers for drug delivery

Sagar R Mudshinge  1 , Amol B Deore, Sachin Patil, Chetan M Bhalgat
Affiliations

Nanoparticles: Emerging carriers for drug delivery

Sagar R Mudshinge et al. Saudi Pharm J. 2011 Jul.

Abstract

The core objective of nanoparticles is to control and manipulate biomacromolecular constructs and supramolecular assemblies that are critical to living cells in order to improve the quality of human health. By definition, these constructs and assemblies are nanoscale and include entities such as drugs, proteins, DNA/RNA, viruses, cellular lipid bilayers, cellular receptor sites and antibody variable regions critical for immunology and are involved in events of nanoscale proportions. The emergence of such nanotherapeutics/diagnostics will allow a deeper understanding of human longevity and human ills that include cancer, cardiovascular disease and genetic disorders. A technology platform that provides a wide range of synthetic nanostructures that may be controlled as a function of size, shape and surface chemistry and scale to these nanotechnical dimensions will be a critical first step in developing appropriate tools and a scientific basis for understanding nanoparticles.

Keywords: Biomacromolecular; Diagnostics; Nanoparticles; Nanoscale; Nanostructures; Supramolecular.

PubMed Disclaimer

References

    1. Abeylath S.C., Turos E., Dickey S., Lim D.V. Glyconanobiotics: novel carbohydrated nanoparticle antibiotics for MRSA and Bacillus anthracis. Bioorg. Med. Chem. 2008;16(5):2412–2418. - PMC - PubMed
    1. Abhilash M. Potential applications of Nanoparticles. Int. J. Pharm.Bio Sci. 2010;1(1):1–12.
    1. Agrawal A., Tripp R.A., Anderson L.J., Nie S.M. Real-time detection of virus particles and viral protein expression with two-color nanoparticle probes. J. Virol. 2005;79(13):8625–8628. - PMC - PubMed
    1. Akerman M.E., Chan W.C.W., Laakkonen P., Bhatia S.N., Ruoslahti E. Nanocrystal targeting in vivo. Proc. Natl. Acad. Sci. USA. 2002;99(20):12617–12621. - PMC - PubMed
    1. Alivisatos P. The use of nanocrystals in biological detection. Nat. Biotechnol. 2004;22(1):47–52. - PubMed

LinkOut - more resources