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. 2013 Jul;21(3):245-53.
doi: 10.1016/j.jsps.2012.05.011. Epub 2012 Jun 23.

Adenosine and its receptors as therapeutic targets: An overview

Sakshi Sachdeva  1 , Monika Gupta
Affiliations

Adenosine and its receptors as therapeutic targets: An overview

Sakshi Sachdeva et al. Saudi Pharm J. 2013 Jul.

Abstract

The main goal of the authors is to present an overview of adenosine and its receptors, which are G-protein coupled receptors. The four known adenosine receptor subtypes are discussed along with the therapeutic potential indicating that these receptors can serve as targets for various dreadful diseases.

Keywords: A1, A2A, A2B, A3 receptors; Adenosine; Purine ribonucleosides.

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Figures

Figure 1
Figure 1
Structure of adenosine.
Figure 2
Figure 2
Adenosine formation and catabolism.
Figure 3
Figure 3
Intracellular and extracellular balancing system of adenosine.
Figure 4
Figure 4
Adenosine receptor model (Figure adapted from Hitchinson et al., 2006).
None
See this image and copyright information in PMC

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