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. 2011 Jul;25(3):305-8.
doi: 10.1016/j.sjopt.2011.03.001. Epub 2011 Mar 15.

Peripheral sterile corneal infiltrate in two brothers after photorefractive keratectomy

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Peripheral sterile corneal infiltrate in two brothers after photorefractive keratectomy

Abdulrahman Al-Muammar. Saudi J Ophthalmol. 2011 Jul.

Abstract

This is a report of two brothers who underwent bilateral photorefractive keratectomy and developed bilateral peripheral corneal infiltrate on the third day following surgery. The patients were treated with antibiotics and low concentration steroid until negative culture was reported 48 h later, when intensive topical steroid was started. The infiltrate resolved by day 10 with residual subepithelial haze that was apparent 8 months after surgery. Sterile infiltrate has been reported as complication of photorefractive keratectomy and can be managed successfully with excellent outcome. The fact that it happened in two brothers may raise the possibility of genetic predisposition.

Keywords: Bandage contact lenses; Corneal infiltrate; Nonsteroidal anti-inflammatory drug; Photorefractive keratectomy; Sterile infiltrate.

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Figures

Figure 1
Figure 1
Case 1: slit lamp photography of the right eye 5 days after PRK. Note the incomplete ring shaped creamy white infiltrate outside treatment zone.
Figure 2
Figure 2
Case 2: slitlamp photography of the left eye 5 days after PRK. Note the incomplete ring shaped creamy white infiltrate outside treatment zone.

References

    1. Ambrosio R.J., Periman L.M., Netto M.V., Wilson S.E. Bilateral marginal sterile infiltrates and diffuse lamellar keratitis after laser in situ keratomileusis. J. Refract. Surg. 2003;19:154–158. - PubMed
    1. Baum J., Dabezies O.H., Jr. Pathogenesis and treatment of “sterile” midperipheral corneal infiltrates associated with soft contact lens use. Cornea. 2000;19(6):777–781. - PubMed
    1. Donshik P.C., Suchecki J.K., Ehlers W.H. Peripheral corneal infiltrates associated with contact lens wear. Trans. Am. Ophthalmol. Soc. 1995;93:49–60. discussion 4. - PMC - PubMed
    1. Haw W.W., Manche E.E. Sterile peripheral keratitis following laser in situ keratomileusis. J. Refract. Surg. 1999;15:61–63. - PubMed
    1. Ku E.C., Lee W., Kothari H.V., Scholer D.W. Effect of diclofenac sodium on the arachidonic acid cascade. Am. J. Med. 1986;80(4B):18–23. - PubMed

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