Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Jul 26:7:34-41.
doi: 10.2174/1874364101307010034. eCollection 2013.

Morphology of optic disc through heidelberg retina tomograph in retinal vein occlusions alone or in combination with primary open angle glaucoma

Alessandro Guido Actis  1 , Luca Belli, Laura Dall'orto, Rachele Penna, Beatrice Brogliatti, Teresa Rolle
Affiliations

Morphology of optic disc through heidelberg retina tomograph in retinal vein occlusions alone or in combination with primary open angle glaucoma

Alessandro Guido Actis et al. Open Ophthalmol J. .

Abstract

Purpose: To evaluate the morphology of optic discs in eyes suffering from retinal vein occlusion (RVO) alone or in combination with primary open-angle glaucoma (POAG).

Methods: Prospective, observational study. 48 consecutive patients were enrolled, 30 with unilateral RVO diagnosis, 18 with unilateral retinal vein occlusion (RVO) associated with POAG. We divided RVOs on the basis of occlusion site: arterio-venous crossing (AV-RVO), optic cup (OC-RVO), optic nerve (ON-RVO) with head nerve swelling (ONHS-RVO) or without it (NONHS-RVO). A control group of 25 patients who were sex and age matched was selected.

Results: Comparing the fellow eyes of the patients with RVO and control healthy eyes, no differences emerged in cup/disc ratio but they came out for the HRT values in Rim Area, cup shape measure and height variation contour (p<0.05). The most frequent occlusion site was at the level of an arteriovenous crossing in patients not suffering from POAG (36.7%) and at the level of the optic cup in patients with RVO and POAG (50%). In the RVO group without POAG, the OC-RVO subgroup has shown an higher cup area (0.366±0.094) and cup/disc area ratio (0.184±0.063), a lower rim volume (0.374±0.021) and a different cup shape measure (-0.221±0.066) (p<0.05) compared with the AV and NONHS sites. Compared with NONHS group differences emerged also for the fibres parameters and in the height variation contour (0.346±0.081). Also in the RVO group with POAG significant differences (p<0.05) have been surveyed between OC-RVO and other occlusion sites in cup area (0.119±0.029), cup/disc area ratio (0.532±0.09), rim volume (0.374±0.07), cup/shape measure (-0.079±0.013).

Conclusions: Classification of the analyzed parameters on the basis of the occlusion site provides a basis for which clinical decisions and research on causal factors in future studies can be based on.

Keywords: HRT.; Optic disc; glaucoma; retinal vein occlusion (RVO).

PubMed Disclaimer

Figures

Fig. (1)
Fig. (1)
Frequency of the occlusion sites of RVO group without POAG.
Fig. (2)
Fig. (2)
Frequency of the occlusion sites of RVO group with POAG.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Hahn P, Fekrat S. Best practices for treatment of retinal vein occlusion. Curr Opin Ophthalmol. 2012;23(3):175–81. - PubMed
    1. Tuulonen A, Airaksinen PJ, Erola E, et al. The finnish evidence-based guideline for open angle glaucoma. Acta Ophthalmol Scand. 2003;81:3–18. - PubMed
    1. European Glaucoma Society. Terminology and Guidelines for Glaucoma. 3rd ed. Savona (Italia): Dogma Editrice; 2008.
    1. Chauhan BC, Mikelberg FS, Balaszi AG, Le Blanc RP, Leske MR, Trope GE. Canadian glaucoma study: risk factors for the progression of open angle glaucoma. Arch Ophthalmol. 2008;126(8):1030–6. - PubMed
    1. Kim MJ, Woo SJ, Park KH, Kim TW. Retinal nerve fiber layer thickness is decreased in the fellow eyes of patients with unilateral retinal vein occlusion. Ophthalmology. 2011;118(4):706–10. - PubMed

LinkOut - more resources