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. 2013 Dec;47(3):559-62.
doi: 10.1007/s11262-013-0953-8. Epub 2013 Aug 21.

Detection and genetic characterization of feline kobuviruses

Joon-Yee Chung  1 , Seong-Hee Kim, Yeon-Hee Kim, Myoung-Heon Lee, Kyoung-Ki Lee, Jae-Ku Oem
Affiliations

Detection and genetic characterization of feline kobuviruses

Joon-Yee Chung et al. Virus Genes. 2013 Dec.

Abstract

In order to survey for feline kobuviruses infection, fecal samples (n = 39) of cats with diarrhea were collected during 2011-2012. Six (14.5%) of the fecal samples tested were positive for feline kobuviruses. The partial nucleotide sequences of feline kobuviruses based on the RNA-dependent RNA polymerase gene were compared to those of other species. Feline kobuviruses were most closely related to canine kobuvirus in terms of their amino acid and nucleotide levels. In a phylogenetic tree, feline kobuviruses were also closely clustered with canine kobuvirus, Aichi virus (human), and mouse kobuvirus. This is the first report of the detection and genetic characterization of feline kobuviruses.

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Figures

Fig. 1
Fig. 1
Phylogenetic relationship between the partial RdRp nucleotide sequences (454 bp in length) from 22 kobuvirus strains from 9 species. Foot-and-mouth disease virus (GenBank accession no. X00871) was specified as the outgroup. The tree was generated using the neighbor-joining method. Statistical support was provided by bootstrapping with 1,000 replicates
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