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. 2013 Aug 20;110(34):13695.
doi: 10.1073/pnas.1314120110.

Antibody-drug conjugates

Stephen Ornes

Antibody-drug conjugates

Stephen Ornes. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

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Antibodies (yellow and blue) can be engineered to carry a cytotoxic drug and deposit it in the target cell. © iStockphoto.com/Eraxion.
See this image and copyright information in PMC

References

    1. FDA (2011) FDA news release: “FDA approves Adcetris to treat two types of lymphoma.” Available at www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm268781.htm. Accessed September 15, 2012.
    1. Younes A, et al. Results of a pivotal phase II study of brentuximab vedotin for patients with relapsed or refractory Hodgkin’s lymphoma. J Clin Oncol. 2012;30(18):2183–2189. - PMC - PubMed
    1. Verma S, et al. EMILIA Study Group Trastuzumab emtansine for HER2-positive advanced breast cancer. N Engl J Med. 2012;367(19):1783–1791. - PMC - PubMed
    1. FDA (2010) FDA news Release: “Pfizer voluntarily withdraws cancer treatment Mylotarg from U.S. market.” Available at www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm216448.htm. Accessed September 15, 2012.

MeSH terms

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