Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013;19(9):1528-30.
doi: 10.3201/eid1909.130013.

Hepatitis E virus genotype 4, Nanjing, China, 2001-2011

Xing Dai, Chen Dong, Zhenxian Zhou, Jiuhong Liang, Min Dong, Yan Yang, Jianguang Fu, Hua Tian, Song Wang, Jie Fan, Jihong Meng, Michael A Purdy

Hepatitis E virus genotype 4, Nanjing, China, 2001-2011

Xing Dai et al. Emerg Infect Dis. 2013.

Abstract

During 2001-2011, hepatitis E virus (HEV) was found in the blood of patients in Nanjing, China. All HEV-positive patients had virus genotype 4; subgenotype 4a was predominant. The effective population of HEV in Nanjing increased in ≈1980 and continued until ≈2003 when it plateaued.

Keywords: China; Nanjing; acute infection; evolution; genotype 4; hepatitis E; hepatitis E virus; viruses.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Hepatitis E virus (HEV) RNA–positive patients at Affiliated Second Hospital, Nanjing, China. Data for 2011 are for the first 4 months of the year only.
Figure 2
Figure 2
Effective populations of hepatitis E virus, Nanjing, China, calculated from sequences with known years of collection. Solid black line, mean effective population; dashed black line, median effective population; gray lines, the upper and lower limits of the 95% highest posterior density. Ne is the effective population with HEV, and τ is the generation time of the virus in years.
See this image and copyright information in PMC

References

    1. Emerson SU, Anderson D, Arankalle A, Meng XJ, Purdy MA, Schlauder GG, et al. Hepevirus. In: Fauquet CM, Mayo MA, Maniloff J, Desselberger U, Ball LA, editors. Virus taxonomy: eighth report of the International Committee on Taxonomy of Viruses. London: Elsevier/Academic Press; 2004. p. 853–7.
    1. Krawczynski K, Kamili S, Aggarwal R. Global epidemiology and medical aspects of hepatitis E. Forum (Genova). 2001;11:166–79 . - PubMed
    1. Okamoto H. Genetic variability and evolution of hepatitis E virus. Virus Res. 2007;127:216–28. 10.1016/j.virusres.2007.02.002 - DOI - PubMed
    1. Lewis HC, Wichmann O, Duizer E. Transmission routes and risk factors for autochthonous hepatitis E virus infection in Europe: a systematic review. Epidemiol Infect. 2010;138:145–66. 10.1017/S0950268809990847 - DOI - PubMed
    1. Purdy MA, Khudyakov YE. The molecular epidemiology of hepatitis E virus infection. Virus Res. 2011;161:31–9. 10.1016/j.virusres.2011.04.030 - DOI - PubMed

Publication types

Associated data

LinkOut - more resources