Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2013 Nov;51(11):3852-4.
doi: 10.1128/JCM.01618-13. Epub 2013 Aug 21.

Comparison of matrix-assisted laser desorption ionization-time of flight (maldi-tof) mass spectrometry platforms for the identification of gram-negative rods from patients with cystic fibrosis

Affiliations
Comparative Study

Comparison of matrix-assisted laser desorption ionization-time of flight (maldi-tof) mass spectrometry platforms for the identification of gram-negative rods from patients with cystic fibrosis

Kevin Alby et al. J Clin Microbiol. 2013 Nov.

Abstract

We evaluated the performance of the Bruker Biotyper and the bioMérieux Vitek MS with both the SARAMIS v4.09 and Knowledge Base v2.0 databases for the identification of 203 non-glucose-fermenting Gram-negative rods that had previously been identified by 16S rRNA gene sequencing. Including those that underwent repeat testing, 96.6%, 90.1%, and 93.6% of isolates, respectively, had identifications that agreed with the previous identification.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Patel R. 2013. Matrix-assisted laser desorption ionization-time of flight mass spectrometry in clinical microbiology. Clin. Infect. Dis. 57:564–572 - PubMed
    1. Westblade LF, Jennemann R, Branda J, Bythrow M, Ferraro MJ, Garner OB, Ginocchio CC, Lewinski M, Manji R, Mochon B, Procop GW, Richter SS, Rychert J, Sercia L, Burnham C-AD. 2013. Multicenter study evaluating the VITEK MS for identification of medically important yeasts. J. Clin. Microbiol. 51:2267–2272 - PMC - PubMed
    1. McElvania TeKippe E, Shuey S, Winkler DW, Butler MA, Burnham C-AD. 2013. Optimizing identification of clinically relevant gram-positive organisms by use of the Bruker Biotyper matrix-assisted laser desorption ionization-time of flight mass spectrometry system. J. Clin. Microbiol. 51:1421–1427 - PMC - PubMed
    1. LiPuma JJ. 2010. The changing microbial epidemiology in cystic fibrosis. Clin. Microbiol. Rev. 23:299–323 - PMC - PubMed
    1. Tan KE, Ellis BC, Lee R, Stamper PD, Zhang SX, Carroll KC. 2012. Prospective evaluation of a matrix-assisted laser desorption ionization-time of flight mass spectrometry system in a hospital clinical microbiology laboratory for identification of bacteria and yeasts: a bench-by-bench study for assessing the impact on time to identification and cost-effectiveness. J. Clin. Microbiol. 50:3301–3308 - PMC - PubMed

MeSH terms