Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Aug 22;500(7463):395-6.
doi: 10.1038/500395a.

Medical research: Trial unpredictability yields predictable therapy gains

Benjamin Djulbegovic  1 , Ambuj Kumar, Paul Glasziou, Branko Miladinovic, Iain Chalmers
Affiliations

Medical research: Trial unpredictability yields predictable therapy gains

Benjamin Djulbegovic et al. Nature. .

Abstract

In decades of clinical-trial data, new treatments are better than standard ones just over half the time. That's as it should be, say Benjamin Djulbegovic and colleagues.

PubMed Disclaimer

References

    1. Evans I, Thornton H, Chalmers I, Glasziou P. Testing Treatments: Better Research for Better Healthcare. 2nd. Pinter & Martin; 2011. - PubMed
    1. Micheel CM, Nass SJ, Omenn GS, editors. Evolution of Translational Omics: Lessons Learned and the Path Forward. National Academies Press; 2012. - PubMed
    1. Glasziou P, Chalmers I, Rawlins M, McCulloch P. Br Med J. 2007;334:349–351. - PMC - PubMed
    1. Djulbegovic B. J Med Philos. 2007;32:79–98. - PubMed
    1. Chalmers I. Br Med J. 1997;314:74–75. - PMC - PubMed

MeSH terms