News and views: at long last, an animal model of Graves' orbitopathy
- PMID: 23975854
- PMCID: PMC3749473
- DOI: 10.1210/en.2013-1705
News and views: at long last, an animal model of Graves' orbitopathy
Comment on
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Cutting edge: retrobulbar inflammation, adipogenesis, and acute orbital congestion in a preclinical female mouse model of Graves' orbitopathy induced by thyrotropin receptor plasmid-in vivo electroporation.Endocrinology. 2013 Sep;154(9):3008-15. doi: 10.1210/en.2013-1576. Epub 2013 Jul 30. Endocrinology. 2013. PMID: 23900776
References
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- Eckstein AK, Plicht M, Lax H, et al. Thyrotropin receptor autoantibodies are independent risk factors for Graves' ophthalmopathy and help to predict severity and outcome of the disease. J Clin Endocrinol Metab. 2006;91:3464–3470 - PubMed
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- Lytton SD, Ponto KA, Kanitz M, Matheis N, Kohn LD, Kahaly GJ. A novel thyroid stimulating immunoglobulin bioassay is a functional indicator of activity and severity of Graves' orbitopathy. J Clin Endocrinol Metab. 2010;95:2123–2131 - PubMed
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- Khoo DH, Eng PH, Ho SC, et al. Graves' ophthalmopathy in the absence of elevated free thyroxine and triiodothyronine levels: prevalence, natural history, and thyrotropin receptor antibody levels. Thyroid. 2000;10:1093–1100 - PubMed
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