Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Mar;2(2):163-8.
doi: 10.3978/j.issn.2225-319X.2013.03.03.

Consensus on hypothermia in aortic arch surgery

Affiliations

Consensus on hypothermia in aortic arch surgery

Tristan D Yan et al. Ann Cardiothorac Surg. 2013 Mar.

Abstract

Considered a standard part of aortic arch surgery, hypothermia can sufficiently reduce cerebral metabolic demand to permit reasonable periods of circulatory arrest. Yet despite its ubiquitous application and critical importance, temperature classification in hypothermic circulatory arrest is still without clear definition. The following Consensus from experts in high-volume aortic institutions defines 'profound', 'deep', 'moderate', and 'mild' hypothermia and recommends standardized monitoring sites, so as to facilitate more consistent reporting and robust analysis.

Keywords: Aortic arch surgery; cerebral protection; consensus statement; hypothermic circulatory arrest.

PubMed Disclaimer

Figures

Figure 1
Figure 1
The proportion of patients for whom electrocerebral silence is achieved at a given nasopharyngeal temperature. Proposed categories are superimposed in dark red. (Modified from Stecker et al.)
Figure 2
Figure 2
Cumulative probability representation that electrocerebral silence (ECS) is not achieved for temperatures above that indicated. For example, at 20 °C, 75% of patients have not achieved ECS. Proposed categories are superimposed in dark red. (Modified from Stecker et al.)
Figure 3
Figure 3
Cerebral metabolic rate, as percentage of baseline, at various esophageal temperatures, and estimated safe duration of HCA. Proposed categories are superimposed in dark red. (Modified from McCullough et al.)
Figure 4
Figure 4
Temperature variations at various sites as compared to the brain during cerebral aneurysm repair. Each coloured bar represents change compared to brain temperature at various stages of cooling. The esophageal temperature most closely resembles cortical temperature, followed by the pulmonary artery and nasopharyngeal temperature. The rectum and bladder are considerably warmer than the brain during cooling and cooler during rewarming, while the opposite is true for the perfusate temperature (Modified from Stone et al.)

References

    1. Kamiya H, Hagl C, Kropivnitskaya I, et al. The safety of moderate hypothermic lower body circulatory arrest with selective cerebral perfusion: a propensity score analysis. J Thorac Cardiovasc Surg 2007;133:501-9 - PubMed
    1. Stecker MM, Cheung AT, Pochettino A, et al. Deep hypothermic circulatory arrest: I. Effects of cooling on electroencephalogram and evoked potentials. Ann Thorac Surg 2001;71:14-21 - PubMed
    1. Andersen ND, James ML, Swaminathan M, et al. Predictors of electrocerebral inactivity with deep hypothermia. J Thorac Cardiovasc Surg. 2013 [Epub ahead of print] - PMC - PubMed
    1. McCullough JN, Zhang N, Reich DL, et al. Cerebral metabolic suppression during hypothermic circulatory arrest in humans. Ann Thorac Surg 1999;67:1895-9; discussion 1919-21. - PubMed
    1. Svensson LG, Crawford ES, Hess KR, et al. Deep hypothermia with circulatory arrest. Determinants of stroke and early mortality in 656 patients. J Thorac Cardiovasc Surg 1993;106:19-28; discussion 28-31 - PubMed