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Case Reports
. 2013 Mar 30:2:34.
doi: 10.4103/2277-9175.109719. eCollection 2013.

Case report of the extramedullary hematopoiesis presented as a hypervascular intracranial mass

Affiliations
Case Reports

Case report of the extramedullary hematopoiesis presented as a hypervascular intracranial mass

Nazila Tayari et al. Adv Biomed Res. .

Abstract

Thalassemia is a hematologic disorder that causes ineffective hematopoiesis and is related to severe anemia, iron overload, extramedullary hematopoiesis, and hepatomegaly. Hepatomegaly is related to significant extramedullary hematopoiesis. The other sites that are involved in extramedullary hematopoiesis are spleen, lymph nodes, paraspinal regions, kidney, pleura, and intestine, but intracranial involvement is a rare presentation. We discuss about a case with intracranial medullary hematopoiesis in a thalassemic patient.

Keywords: Cerebral ventricle; extra medullary hematopoiesis; paraventricle.

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Conflict of interest statement

Conflict of Interest: None declared

Figures

Figure 1
Figure 1
AP skull X-ray showing thickening of diploic space
Figure 2
Figure 2
Lateral skull X-ray showing thickening of diploic space
Figure 3
Figure 3
Brain CT scan (bony window) showing external and internal skull Tables and diploic space thickening
Figure 4
Figure 4
Brain CT scan (soft tissue window) showing a hyperdense paraventricular mass with peripheral edema
Figure 5
Figure 5
Contrast-enhanced brain CT scan showing an intense enhancible paraventricular mass
Figure 6
Figure 6
Axial T1-W brain MRI revealing a hyperintense paraventricular mass
Figure 7
Figure 7
Axial T2-W brain MRI showing a hypointense paraventricular mass with hyperintense peripheral edema
Figure 8
Figure 8
Sagittal contrast-enhanced T1-W brain MRI revealing an intense homogeneous enhancible paraventricular mass

References

    1. Haidar S. Intracranial involvement in extramedullary hematopoiesis: Case report and review of the literature. Pediatr Radiol. 2005;35:630–4. - PubMed
    1. Papavasiliou C. Clinical expressions of the expansion of the bone marrow in the chronic anemias: The role of radiotherapy. Int J Radiat Oncol Biol Phys. 1994;28:605–12. - PubMed
    1. Ohtsubo M, Hayashi K, Fukushima T, Chiyoda S, Takahara O. Intracranial extramedullary haematopoiesis in postpolycythemic myelofibrosis. Br J Radiol. 1994;67:299–302. - PubMed
    1. Sanei Taheri M, Birang SH, Shahnazi M, Hemadi H. Large Splenic Mass of Extramedullary Hematopoiesis. Iran J Radiol. 2005;2:99–101.
    1. Singer A, Maldjian P, Simmons M. Extramedullary hematopoiesis presenting as a focal splenic mass: Case report. Abdom Imaging. 2004;29:710–2. - PubMed

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