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Comparative Study
. 2013 Dec;62(6):552-3.
doi: 10.1016/j.parint.2013.08.008. Epub 2013 Aug 24.

The rapid detection of Cryptosporidium and Giardia species in clinical stools using the Quik Chek immunoassay

Claire L Alexander  1 , Marc Niebel, Brian Jones
Affiliations
Comparative Study

The rapid detection of Cryptosporidium and Giardia species in clinical stools using the Quik Chek immunoassay

Claire L Alexander et al. Parasitol Int. 2013 Dec.

Abstract

Diagnostic testing in the United Kingdom for Cryptosporidium and Giardia species is routinely performed by microscopy. In this study, two hundred stool samples from human clinical cases were examined for the presence of these two parasites comparing microscopy with an antigen immunoassay, Quik Chek (Techlab, Inc.). The Quik Chek assay was shown to have a sensitivity and specificity for Cryptosporidium detection of 87.6% and 98.9% respectively and for Giardia detection, 93.3% and 99.4% respectively. The high correlation with microscopy data provides evidence to support implementation of this rapid test within diagnostic microbiology laboratories.

Keywords: Cryptosporidium; Giardia; Immunoassay; Microscopy; Rapid.

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