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. 2012 Apr;2(2):85-9.
doi: 10.1177/2045125311433581.

Risperidone-induced acromegaly: a case report

Ayşe Koroglu, Cicek Hocaoglu

Risperidone-induced acromegaly: a case report

Ayşe Koroglu et al. Ther Adv Psychopharmacol. 2012 Apr.

Abstract

Today, considering their adverse side effects, the first-generation antipsychotics have been replaced by the new-generation antipsychotics (also known as second-generation antipsychotic agents). The superiority of new-generation antipsychotics compared with first-generation antipsychotic agents in terms of side effects, especially movement disorders, are acknowledged by clinicians. But in recent years during the use of second-generation antipsychotic agents, endocrine side effects have been noteworthy. In our study with a diagnosis of paranoid schizophrenia treated with risperidone for 14 years and operated with the diagnosis of pituitary macroadenoma, a 32-year-old female patient is presented in the light of the literature examining the framework of the history of disease.

Keywords: acromegaly; endocrine side effects; risperidone.

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Conflict of interest statement

The authors declare no conflicts of interest in preparing this article.

References

    1. Blanc O., Brousse G., Meary A. (2010) Pharmacogenetic of response efficacy to antipsychotics in schizophrenia: pharmacodynamic aspects. Review and implications for clinical research. Fundamental Clin Pharmacol 24: 139–160 - PubMed
    1. Coccurello R., Moles A. (2010) Potential mechanisms of atypical antipsychotic-induced metabolic derangement: clues for understanding obesity and novel drug design. Pharmacol Ther 127: 210–251 - PubMed
    1. Debono M., Newell-Price J. (2010) New formulations and approaches in the medical treatment of acromegaly. Curr Opin Endocrinol Diabetes Obes 17: 350–355 - PubMed
    1. Erer S., Yilmazlar S., Zarifoglu M., Guclu M. (2008) A case report on pituitary macroadenoma presented as hemichorea hemiballism syndrome. Dialogues Clin Neurosci 29: 289–290 - PubMed
    1. Gianfrancesco F.D., Pandina G., Mahmoud R., Wu J., Wang R. (2009) Potential bias in testing for hyperprolactinemia and pituitary tumors in risperidone-treated patients: a claims-based study. 11: 5–8 - PMC - PubMed

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