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Comment
. 2013 Sep;45(9):965-7.
doi: 10.1038/ng.2738.

Cholesterol metabolism and Rett syndrome pathogenesis

Gabor Nagy, Susan L Ackerman
Comment

Cholesterol metabolism and Rett syndrome pathogenesis

Gabor Nagy et al. Nat Genet. 2013 Sep.

Abstract

Rett syndrome is caused by mutations in the gene encoding the transcriptional regulator MECP2. A new study demonstrates that cholesterol homeostasis is disrupted in Mecp2 mutant mice and suggests new therapeutic options for this disease.

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