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Comment
. 2013 Sep;45(9):967-8.
doi: 10.1038/ng.2737.

A developmental program for Candida commensalism

Neil A R Gow
Comment

A developmental program for Candida commensalism

Neil A R Gow. Nat Genet. 2013 Sep.

Abstract

Candida albicans is a frequent pathogen of immunologically compromised individuals, but it is an even more common commensal of healthy humans, where it resides in the gut in a benign state. A new study shows that a specific commensal form of the fungus is induced in the gut through a developmental program that downregulates virulence factors and induces metabolic functions, enabling it to thrive on the nutrients that are available in the large intestine without damaging its host.

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References

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