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. 1975 Aug 15;31(8):964-5.
doi: 10.1007/BF02358879.

Gastric secretion during anaesthesia and its inhibition by metiamide and other drugs

M Schachter, E Karpinski, V Haines

Gastric secretion during anaesthesia and its inhibition by metiamide and other drugs

M Schachter et al. Experientia. .

Abstract

The histamine H2-receptor antagonist, metiamide, inhibits the acid gastric secretion produced by chloralose-urethane anaesthesia in dogs carrying gastric cannulae chronically. This secretion is also prevented by atropine and hexamethonium. "Spontaneous" gastric secretion of vagal origin in conscious dogs is also blocked by metiamide.

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References

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