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. 2013 Aug 30:2013:0918.

Amoebic dysentery

Chelsea Marie  1 , William Arthur Petri Jr
Affiliations

Amoebic dysentery

Chelsea Marie et al. BMJ Clin Evid. .

Abstract

Introduction: Amoebic dysentery is caused by the protozoan parasite Entamoeba histolytica. It is transmitted in areas where poor sanitation allows contamination of drinking water and food with faeces. In these areas, up to 40% of people with diarrhoea may have amoebic dysentery.

Methods and outcomes: We conducted a systematic review and aimed to answer the following clinical question: What are the effects of drug treatments for amoebic dysentery in endemic areas? We searched: Medline, Embase, The Cochrane Library, and other important databases up to June 2013 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).

Results: We found 6 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.

Conclusions: In this systematic review, we present information relating to the effectiveness and safety of the following interventions: diiodohydroxyquinoline (iodoquinol), diloxanide, emetine, metronidazole, nitazoxanide, ornidazole, paromomycin, secnidazole, and tinidazole.

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References

    1. Last JM (ed). A dictionary of epidemiology. 3rd ed. New York, NY: Oxford University Press; 1995.
    1. Rivera WL, Tachibana H, Kanbara H. Field study on the distribution of Entamoeba histolytica and Entamoeba dispar in the northern Philippines as detected by the polymerase chain reaction. Am J Trop Med Hyg 1998;59:916–921. - PubMed
    1. Haque R, Faruque ASG, Hahn P, et al. Entamoeba histolytica and Entamoeba dispar infection in children in Bangladesh. J Infect Dis 1997;175:734–736. - PubMed
    1. Braga LL, Mendonca Y, Paiva CA, et al. Seropositivity for and intestinal colonization with Entamoeba histolytica and Entamoeba dispar in individuals in Northeastern Brazil. J Clin Microbiol 1998;36:3044–3045. - PMC - PubMed
    1. Chacin-Bonilla L, Bonillla E, Parra AM, et al. Prevalence of Entamoeba histolytica and other intestinal parasites in a community from Maracaibo, Venezuela. Ann Trop Med Parasitol 1992;86:373–380. - PubMed

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