Teratocarcinoma in a non seminomatous, mixed germ cell tumour of the testis-a rare entity
- PMID: 23998086
- PMCID: PMC3749656
- DOI: 10.7860/JCDR/2013/5404.3161
Teratocarcinoma in a non seminomatous, mixed germ cell tumour of the testis-a rare entity
Abstract
Mixed Germ Cell Tumours (MGCTs) of the testis are the second most common testicular tumours. In the 10 years retrospective study which was done on testicular neoplasms at our institute, this reported case accounted for 0.4%. We are presenting the case of a 30 year old male with a painless testicular swelling. Abdominal ultrasonography disclosed it as a seminoma and the FNAC report was Mixed Germ Cell tumour of the testis. Histopathology concurred the cytological diagnosis and it additionally revealed the concomitant presence of a Yolk Sac Tumour (YST) and a Teratocarcinoma in a Non-Seminomatous Tumour of the testis. This case attains uniqueness with the very rare presence of the yolk sac tumour with the teratocarcinoma component in Non-Seminomatous Testicular Tumours. The reason behind the reporting of the case was its poor therapeutic response.
Keywords: MGCT; Non seminomatous testicular tumour; Teratocarcinoma; YST.
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References
-
- Parkin DM, Bray F, Ferlay J, Pisani P. Global Cancer Statistics. 2002 - PubMed
-
- Eble JN, Sauter G, Epstein JI, Sesterhenn I. Tumors of the urinary system and male genital organs. Lyon, France: IARC Press; 2004. WHO Classification of tumors. Pathology and Genetics.
-
- Damjanov Ivan, Linder James. Anderson’s Pathology. (10e) 2009;2:2184–85.
-
- Mosharafa Ashraf A, Foster Richard S, Leibovich Bradley C, Ulbright Thomas M, et al. Histology in mixed germ cell tumor. Is there a favorite pairing. The journal of Urology. 2004;171:1471–73. - PubMed
-
- Talerman A MD. The incidence of Yolk sac tumor elements in germ cell tumor of testis in adults. Cancer. 1975;36:211–15. - PubMed
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