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Randomized Controlled Trial
. 2013 Oct;29(5):239-46.
doi: 10.1111/phpp.12061.

BB-UVA vs. NB-UVB in the treatment of vitiligo: a randomized controlled clinical study (single blinded)

Medhat El-Mofty  1 , Wedad Mostafa, Randa Youssef, Mona El-Fangary, Amany El-Ramly, Doaa Mahgoub, Marwa Fawzy, Marwa El-Hawary
Affiliations
Randomized Controlled Trial

BB-UVA vs. NB-UVB in the treatment of vitiligo: a randomized controlled clinical study (single blinded)

Medhat El-Mofty et al. Photodermatol Photoimmunol Photomed. 2013 Oct.

Abstract

Background: Vitiligo is an acquired pigmentary disorder that affects between 1% and 2% of the general population. Phototherapy remains the cornerstone of treatment, with NB-UVB being the most frequently used. BB-UVA can be a plausible alternative for darker population; skin photo type III and IV.

Patients and methods: The study was a prospective, randomized, controlled, and single-blinded clinical trial, conducted on 40 patients with bilateral symmetrical vitiligo. The patients were randomly divided into two equal groups; group (A) received a fixed dose of 15 J/cm(2) BB-UVA, while group (B) received NB-UVB. The study was conducted for a period of 16 weeks (48 sessions).

Results: The final percentage of clinical improvement was significantly higher (P = 0.047) within the BB-UVA group (63.82% ± 27.42), than within the NB-UVB group (44.32% ± 29.78).

Conclusion: BB-UVA can be considered as an alternative treatment line for vitiligo.

Keywords: BB-UVA; NB-UVA; vitiligo.

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