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. 2013 Aug;46(4):256-64.
doi: 10.5090/kjtcs.2013.46.4.256. Epub 2013 Aug 6.

Single and multiple valve surgery in native valve infective endocarditis

Tae Sik Kim  1 , Chan-Young Na, Sam Sae Oh, Jae Hyun Kim, Gil Soo Yie, Jung Wook Han, Min Cheol Chae
Affiliations

Single and multiple valve surgery in native valve infective endocarditis

Tae Sik Kim et al. Korean J Thorac Cardiovasc Surg. 2013 Aug.

Abstract

Background: Surgical treatment of infective endocarditis (IE) remains a challenge, especially in cases of multiple valve surgery. We evaluated the clinical outcomes of native valve IE and compared the outcomes of single valve surgery with those of multiple valve surgery.

Materials and methods: From 1997 to 2011, 90 patients underwent surgery for native valve IE; 67 patients with single valve surgery (single valve group) and 23 patients with multiple valve surgery (multiple valve group). The mean follow-up duration was 73.1±47.4 months.

Results: The surgical mortality in the total cohort was 4.4%. The overall survival (p=0.913) and valve-related event-free survival (p=0.204) did not differ between the two groups. The independent predictor of postoperative complications was New York Heart Association class (p=0.001). Multiple valve surgery was not a significant predictor of surgical mortality (p=0.225) or late mortality (p=0.936). Uncontrolled infection, urgent or emergency surgery, and postoperative complications were identified as independent predictors of valve-related morbidity, excluding multiple valve surgery (p=0.072).

Conclusion: In native valve IE, multiple valve surgery as a factor was not an independent predictor of mortality and morbidity. The number of surgically corrected valves in native IE seems to be unrelated to perioperative and long-term outcomes.

Keywords: Endocarditis; Heart valves; Morbidity; Mortality; Thoracic surgery.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1
The actuarial rate of the overall survival in the single valve and multiple valve groups (log rank, p=0.913).
Fig. 2
Fig. 2
The actuarial valve-related event-free survival in the single valve and multiple valve groups (log rank, p=0.204).
See this image and copyright information in PMC

References

    1. Hoen B, Alla F, Selton-Suty C, et al. Changing profile of infective endocarditis: results of a 1-year survey in France. JAMA. 2002;288:75–81. - PubMed
    1. Selton-Suty C, Doco-Lecompte T, Bernard Y, et al. Clinical and microbiologic features of multivalvular endocarditis. Curr Infect Dis Rep. 2010;12:237–243. - PubMed
    1. Mueller XM, Tevaearai HT, Stumpe F, et al. Multivalvular surgery for infective endocarditis. Cardiovasc Surg. 1999;7:402–408. - PubMed
    1. Gillinov AM, Diaz R, Blackstone EH, et al. Double valve endocarditis. Ann Thorac Surg. 2001;71:1874–1879. - PubMed
    1. Mihaljevic T, Byrne JG, Cohn LH, Aranki SF. Long-term results of multivalve surgery for infective multivalve endocarditis. Eur J Cardiothorac Surg. 2001;20:842–846. - PubMed

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