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Editorial
. 2013 Sep 24;128(13):1400-4.
doi: 10.1161/CIRCULATIONAHA.113.005924. Epub 2013 Sep 4.

R is for arginine: metabolism of arginine takes off again, in new directions

Thomas Michel  1
Affiliations
Editorial

R is for arginine: metabolism of arginine takes off again, in new directions

Thomas Michel. Circulation. .
No abstract available

Keywords: Editorials; amino acids; arginine; nitric oxide; stroke.

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Conflict of interest statement

Conflict of Interest Disclosures: None.

Figures

Figure 1
Figure 1
Principal pathways of arginine and homoarginine metabolism. Please see the text for details and for definition of abbreviations used in this figure.
See this image and copyright information in PMC

Comment on

References

    1. Marletta MA. Nitric oxide: biosynthesis and biological significance. Trends Biochem Sci. 1989;14:488–492. - PubMed
    1. Boger RH, Bode-Boger SM. The clinical pharmacology of L-arginine. Annu Rev Pharm Toxicol. 2001;41:79–99. - PubMed
    1. Vallance T, Leiper J. Cardiovascular biology of the asymmetric dimethylarginine: dimethylaminohydroloase pathway. Arterioscler Thromb Vasc Biol. 2004;24:1023–1030. - PubMed
    1. Caplin B, Leiper J. Endogenous nitric oxide synthase inhibitors in the biology of disease: markers, mediators, and regulators? Arterioscler Thromb Vasc Biol. 2012;32:1343–1353. - PMC - PubMed
    1. Morris SM. Arginine metabolism in vascular biology and disease. Vascular Med. 2005:583–587. - PubMed