Translating the HAPO study into new diagnostic criteria for GDM? From HAPO to IADPSG and back to O'Sullivan

Abstract

The various strategies to diagnose gestational diabetes mellitus (GDM), starting from O'sullivan, followed by numerous opinions and recommendations and up to the recently published International association of diabetes and pregnancy study groups criteria, have been and still are the subject of extensive and ongoing debate, since the 1960s, and holding, fiercely than ever, nowadays. In this review we shall provide an overlook on the history of GDM diagnosis, concentrating on the interpretation of the hyperglycemia and adverse pregnancy outcome results into clinical guidelines, and the pros and cons for changing the criteria for GDM diagnosis.