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Meta-Analysis
. 2014 Sep;35(9):1655-61.
doi: 10.3174/ajnr.A3700. Epub 2013 Sep 5.

MRA versus DSA for follow-up of coiled intracranial aneurysms: a meta-analysis

M J van Amerongen  1 , H D Boogaarts  2 , J de Vries  1 , A L M Verbeek  3 , F J A Meijer  4 , M Prokop  4 , R H M A Bartels  1
Affiliations
Meta-Analysis

MRA versus DSA for follow-up of coiled intracranial aneurysms: a meta-analysis

M J van Amerongen et al. AJNR Am J Neuroradiol. 2014 Sep.

Abstract

MR angiography is proposed as a safer and less expensive alternative to the reference standard, DSA, in the follow-up of intracranial aneurysms treated with endovascular coil occlusion. We performed a systematic review and meta-analysis to evaluate the accuracy of TOF-MRA and contrast-enhanced MRA in detecting residual flow in the follow-up of coiled intracranial aneurysms. Literature was reviewed through the PubMed, Cochrane, and EMBASE data bases. In comparison with DSA, the sensitivity of TOF-MRA was 86% (95% CI: 82-89%), with a specificity of 84% (95% CI: 81-88%), for the detection of any recurrent flow. For contrast-enhanced MRA, the sensitivity and specificity were 86% (95% CI: 82-89%) and 89% (95% CI: 85-92%), respectively. Both TOF-MRA and contrast-enhanced MRA are shown to be highly accurate for detection of any recanalization in intracranial aneurysms treated with endovascular coil occlusion.

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Figures

Fig 1.
Fig 1.
Search results.
Fig 2.
Fig 2.
Pooled sensitivity/specificity in detecting any recurrent flow. A, Sensitivity for TOF-MRA. B, Specificity for TOF-MRA. C, Sensitivity for CE-MRA. D, Specificity for CE-MRA.
Fig 3.
Fig 3.
A, Summary receiver operating characteristic for TOF-MRA. B, Summary receiver operating characteristic for CE-MRA.
See this image and copyright information in PMC

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