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Review
. 2013 Aug;13(4):111-5.
doi: 10.4110/in.2013.13.4.111. Epub 2013 Aug 26.

Osteoimmunology: a brief introduction

Matthew B Greenblatt  1 , Jae-Hyuck Shim
Affiliations
Review

Osteoimmunology: a brief introduction

Matthew B Greenblatt et al. Immune Netw. 2013 Aug.

Abstract

Recent investigations have demonstrated extensive reciprocal interactions between the immune and skeletal systems, resulting in the establishment of osteoimmunology as a cross-disciplinary field. Here we highlight core concepts and recent advances in this emerging area of study.

Keywords: Bone; Cytokines; Osteoblasts; Osteoimmunology; T cells.

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Conflict of interest statement

The authors have no financial conflict of interest.

Figures

Figure 1
Figure 1
A schematic depicting major pathways of interactions between the immune system and bone, highlighting in particular the effects of TNF, IL-1, IL-6, and IL-17 on the promotion of bone resorption. Additionally, anti-osteoclastogenic effects of IFN-γ are depicted.
See this image and copyright information in PMC

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