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. 2013 Winter;4(1):611-6.

C-reactive protein and other markers of inflammation in hemodialysis patients

Affiliations

C-reactive protein and other markers of inflammation in hemodialysis patients

Behzad Heidari. Caspian J Intern Med. 2013 Winter.

Abstract

Hemodialysis patients are at greater risk of cardiovascular disease. Higher than expected cardiovascular morbidity and mortality in this population has been attributed to dislipidemia as well as inflammation. The causes of inflammation in hemodialysis patients are multifactorial. Several markers were used for the detection of inflammatory reaction in patients with chronic renal disease. These markers can be used for the prediction of future cardiovascular events. Among the several parameters of inflammatory markers, serum, CRP is well known and its advantages for the detection of inflammation and its predictor ability has been evaluated in several studies. This review addressed the associated factors and markers of inflammation in hemodialysis patients. In addition, their ability in predicting future atherosclerosis and effect of treatment has been reviewed. However, this context particularly in using CRP as a prediction marker of inflammation and morbidity requires further studies.

Keywords: C-reactive protein; Hemodialysis; Inflammation; Statin.

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References

    1. Yao Q, Pecoits-Filho R, Lindholm B, Stenvinkel P. Traditional and non-traditional risk factors as contributors to atherosclerotic cardiovascular disease in end-stage renal disease. Scand J Urol Nephrol. 2004;38:405–16. - PubMed
    1. Rao M, Jaber BL, Balakrishnan VS. Inflammatory biomarkers and cardiovascular risk: association or cause and effect? Semin Dial. 2006;19:129–35. - PubMed
    1. Nusair MB, Rajpurohit N, Alpert MA. Chronic Inflammation and Coronary Atherosclerosis in Patients with End-Stage Renal Disease. Cardiorenal Med. 2012;2:117–24. - PMC - PubMed
    1. Taylor SP, Taylor BT. Healthcare-associated pneumonia in hemodialysis patients: Clinical outcomes in patients treated with narrow versus broad spectrum antibiotic therapy. Respirology. 2012 Oct 16; doi: 10.1111/j.1440-1843.2012.02306.x. [Epub ahead of print] - PubMed
    1. Yoo HH, Martin LC, Kochi AC, et al. Could albumin level explain the higher mortality in hemodialysis patients with pulmonary hypertension? BMC Nephrol. 2012;13:80. - PMC - PubMed

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