Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2013 Aug;49(2):55-64.
doi: 10.4068/cmj.2013.49.2.55. Epub 2013 Aug 22.

Recent trends in nuclear cardiology practice

Kyoung Sook Won  1 , Bong-Il Song
Affiliations
Review

Recent trends in nuclear cardiology practice

Kyoung Sook Won et al. Chonnam Med J. 2013 Aug.

Abstract

Over the past three decades, radionuclide myocardial perfusion scintigraphy (MPS) has become established as the main functional cardiac imaging technique for ischemic heart disease. It is currently appropriate for all aspects of detecting and managing ischemic heart disease, including diagnosis, risk assessment and stratification, assessment of myocardial viability, and evaluation of left ventricular function. The purpose of this article was to review recent trends in nuclear cardiology practice, excluding positron emission tomography. The past few years have brought several rapid developments that have increased photon sensitivity in nuclear cardiology scanner hardware. Additionally, software applying new methods of single photon emission tomography (SPECT) reconstruction on conventional and dedicated systems has preserved or even improved SPECT image quality with lower count statistics. On the other hand, much interest has been shown in lowering the radiation dose by the stakeholders of MPS.

Keywords: Myocardial perfusion imaging; Radiation; SPECT.

PubMed Disclaimer

Figures

FIG. 1
FIG. 1
D-SPECT cardiac system and detector-head configuration. (A) D-SPECT cardiac scanner with seated patient. (B) Each detector column is composed of CZT sensor (39×39×5 mm) with four 16×16 pixel detectors and tungsten collimator with 0.2-mm septa and square opening (pitch, 2.46 mm; length, 21.7 mm). (C) Nine detector columns, each capable of rotation and translation, are used to scan the myocardium. From Ref. 3.
FIG. 2
FIG. 2
Case example of MPI of a patient with 70% stenosis of the proximal midleft anterior descending coronary artery. (A) Perfusion images by conventional (top) and high-speed (bottom) SPECT demonstrating a moderate reversible perfusion defect in the left anterior descending coronary artery territory. Total acquisition time is indicated on the left-hand side. (B) Quantitative analysis yielded similar results for high-speed and conventional SPECT. From Ref. 5.
FIG. 3
FIG. 3
Proposed algorithm for maximal reduction in patient radiation exposure is modified from ref. 54.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

  • Intranasal delivery of imaging agents to the brain.
    Almahmoud A, Parekh HS, Paterson BM, Tupally KR, Vegh V. Almahmoud A, et al. Theranostics. 2024 Aug 19;14(13):5022-5101. doi: 10.7150/thno.98473. eCollection 2024. Theranostics. 2024. PMID: 39267777 Free PMC article. Review.

References

    1. Health Quality Ontario. Single photon emission computed tomography for the diagnosis of coronary artery disease: an evidence-based analysis. Ont Health Technol Assess Ser. 2010;10:1–64. - PMC - PubMed
    1. 2006 image of the year: focus on cardiac SPECT/CT. J Nucl Med. 2006;47:14N–15N. - PubMed
    1. Gambhir SS, Berman DS, Ziffer J, Nagler M, Sandler M, Patton J, et al. A novel high-sensitivity rapid-acquisition single-photon cardiac imaging camera. J Nucl Med. 2009;50:635–643. - PubMed
    1. Garcia EV, Faber TL, Esteves FP. Cardiac dedicated ultrafast SPECT cameras: new designs and clinical implications. J Nucl Med. 2011;52:210–217. - PubMed
    1. Sharir T, Slomka PJ, Hayes SW, DiCarli MF, Ziffer JA, Martin WH, et al. Multicenter trial of high-speed versus conventional single-photon emission computed tomography imaging: quantitative results of myocardial perfusion and left ventricular function. J Am Coll Cardiol. 2010;55:1965–1974. - PubMed