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Editorial
. 2013 Oct 1;12(19):3133-4.
doi: 10.4161/cc.26353. Epub 2013 Sep 6.

An evolving tail of centromere histone variant CENP-A

Hidenori Kato  1 , Bing-Rui Zhou, Hanqiao Feng, Yawen Bai
Affiliations
Editorial

An evolving tail of centromere histone variant CENP-A

Hidenori Kato et al. Cell Cycle. .
No abstract available

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Figures

None
Figure 1. The C-terminal tail of CENP-A binds to centromere protein CENP-C and chaperone HJURP. (A) Space filling presentation of the overall structure of the rat CENP-C motif in complex with a nucleosome containing the H31–132-IEGGLG chimera. (B) Enlarged illustration of the interactions between the CENP-C motif and the H31–132-IEGGLG nucleosome. Blue and red sticks represent the positively charged Args in the CENP-C motif and the acidic residues in histones H2A and H2B. (C) Amino acid sequences of the CENP-A C-terminal tails in several vertebrate species. (D) Amino acid sequences of the CENP-A C-terminal tails of several yeast species. (E) A structural region of the HJURP/CENP-A/H4 complex, illustrating the electrostatic interactions between HJURP and the C-terminal tail of CENP-A. (F) A region of the Scm3/Cse4/H4 complex corresponding to that in (E), showing that the N-terminal region of Scm3 and the C-terminal region of Cse4 are disordered.
See this image and copyright information in PMC

Comment on

References

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