Heterogeneity and hypothesis testing in neuropsychiatric illness
- PMID: 24013907
- PMCID: PMC3763735
- DOI: 10.1017/S0140525X08004275
Heterogeneity and hypothesis testing in neuropsychiatric illness
Abstract
The confounding effects of heterogeneity in biological psychiatry and psychiatric genetics have been widely discussed in the literature. We suggest an approach in which heterogeneity may be put to use in hypothesis testing and may find application in evaluation of the Crespi and Badcock (C&B) imprinting hypothesis. Here we consider three potential sources of etiologic subtypes for analysis.
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