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Review
. 2013 Apr;3(2):67-76.
doi: 10.4103/2230-973X.114897.

Orally dissolving strips: A new approach to oral drug delivery system

Rajni Bala  1 , Pravin Pawar, Sushil Khanna, Sandeep Arora
Affiliations
Review

Orally dissolving strips: A new approach to oral drug delivery system

Rajni Bala et al. Int J Pharm Investig. 2013 Apr.

Abstract

Recently, fast dissolving films are gaining interest as an alternative of fast dissolving tablets. The films are designed to dissolve upon contact with a wet surface, such as the tongue, within a few seconds, meaning the consumer can take the product without need for additional liquid. This convenience provides both a marketing advantage and increased patient compliance. As the drug is directly absorbed into systemic circulation, degradation in gastrointestinal tract and first pass effect can be avoided. These points make this formulation most popular and acceptable among pediatric and geriatric patients and patients with fear of choking. Over-the-counter films for pain management and motion sickness are commercialized in the US markets. Many companies are utilizing transdermal drug delivery technology to develop thin film formats. In the present review, recent advancements regarding fast dissolving buccal film formulation and their evaluation parameters are compiled.

Keywords: Fast dissolving films; oral mucosa; permeability; solvent casting; solvent casting and disintegration.

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Conflict of interest statement

Conflict of Interest: None declared

Figures

Figure 1
Figure 1
Stages in the development oral solid dosage forms
Figure 2
Figure 2
Evolution of oral thin films
See this image and copyright information in PMC

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