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. 1990 Jun;30(7):428-34.
doi: 10.1111/j.1526-4610.1990.hed3007428.x.

Magnetoencephalographic studies of migraine

G L Barkley  1 , N Tepley, S Nagel-Leiby, J E Moran, R T Simkins, K M Welch
Affiliations

Magnetoencephalographic studies of migraine

G L Barkley et al. Headache. 1990 Jun.

Abstract

We report for the first time the detection by magnetoencephalography (MEG) of signals observable in migraine patients during headache, but not in controls. These signals consisted of three features: suppression of spontaneous cortical activity, long duration field changes, and large amplitude waves (LAW) of several seconds duration. LAW were also seen during the interictal period. We discuss the possible relationship of these signals to spreading depression (SD), and why the LAW have not been observed in previous studies of SD.

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