Thyrotoxicosis in pregnancy:: A case report
Affiliations
- PMID: 24019717
- PMCID: PMC3174707
Item in Clipboard
Thyrotoxicosis in pregnancy:: A case report
J Sci Res Med Sci.
2001 Oct.
Abstract
There are various causes of hyperthyroidism in pregnancy such as Graves' disease and gestational thyrotoxicosis. The thyroid stimulation results from the excessive levels of circulating human chorionic gonadotropin (hCG) produced by the trophoblastic tissue in both hydatidiform moles and choriocarcinoma. We present a pregnant patient with hydatidiform mole who presented with hyperthyroidism that resolved after evacuation of the mole.
Keywords: hCG; hydatidiform mole; pregnancy; thyrotoxicosis.
Similar articles
-
Human chorionic gonadotropin and the thyroid: hyperemesis gravidarum and trophoblastic tumors.Thyroid. 1999 Jul;9(7):653-7. doi: 10.1089/thy.1999.9.653. Thyroid. 1999. PMID: 10447009 Review.
-
Choriocarcinoma as a cause of thyrotoxicosis.Am J Med. 1976 Jun;60(7):1036-40. doi: 10.1016/0002-9343(76)90577-5. Am J Med. 1976. PMID: 945690
-
Gestational trophoblastic diseases - clinical guidelines for diagnosis, treatment, follow-up, and counselling.Dan Med J. 2015 Nov;62(11):A5082. Dan Med J. 2015. PMID: 26522484
-
Diagnosis of hydatidiform mole and persistent trophoblastic disease: diagnostic accuracy of total human chorionic gonadotropin (hCG), free hCG {alpha}- and {beta}-subunits, and their ratios.Eur J Endocrinol. 2005 Oct;153(4):565-75. doi: 10.1530/eje.1.01997. Eur J Endocrinol. 2005. PMID: 16189178
-
Physiological and pathological aspects of the effect of human chorionic gonadotropin on the thyroid.Best Pract Res Clin Endocrinol Metab. 2004 Jun;18(2):249-65. doi: 10.1016/j.beem.2004.03.010. Best Pract Res Clin Endocrinol Metab. 2004. PMID: 15157839 Review.
References
-
- Kimura M, Amino N, Tamaki H, Ito E, Mitsuda N, Miyai K, et al. Gestational thyrotoxicosis and hyperemesis gravidarum, possible role of BhCG with higher stimulating activity. Clin Endocrinol. 1993;38:345–50. - PubMed
-
- Yoshimura M, Hershnan JM. Thyrotropic action of human chorionic gonadotropin. Thyroid. 1995;5:425–34. - PubMed
-
- Yoshimura M, Pekary AE, Pang XP, Berg L, Cole LA, Kardana A, et al. Effect of peptide nicking in the human chorionic gonadotropin beta-subunit on stimulation of recombinant human thyroid-stimulating hormone receptors. Eur J Endocrinol. 1994;130:92–6. - PubMed
-
- Pekary AE, Jackson IM, Goodwin TM, Goodwin TM, Pang XP, Hein MD, et al. Increased in vitro thyrotropic activity in partially sialated human chorionic gonadotropin extracted from hydatidiform moles of patients with hyperthyroidism. J Clin Endocrinol Metab. 1993;76:70–4. - PubMed
-
- Good TM, Heshman JM. Hyperthyroidism due to inappropriate production of human chorionic gonadotropin. Clin Obstet Gynecol. 1997;40:32–44. - PubMed
LinkOut - more resources
Full Text Sources