Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Mar;8(1):68-74.

Functional dyspepsia today

Affiliations

Functional dyspepsia today

Theodor Alexandru Voiosu et al. Maedica (Bucur). 2013 Mar.

Abstract

Functional dyspepsia (FD) is a disorder presenting with symptoms such as postprandial fullness, early satiety or epigastric pain. Although there is a 10 to 30% reported prevalence worldwide, there is currently no clear explanation of the pathophysiology behind this condition. Motility disorders, visceral hypersensitivity, acid disorders, Helicobacter pylori infection or psychosocial factors have all been reported to play a part in the pathophysiology of FD. The diagnosis of FD is one of exclusion, based on the Rome III criteria. The main therapeutic modalities include lifestyle changes, eradicating Helicobacter pylori infection and treatment with either proton pump inhibitors, prokinetics or antidepressants.

PubMed Disclaimer

Figures

Figure 1
Figure 1. Treatment algorithm for FD.

References

    1. Bazaldua OV, Schneider FD. Evaluation and Management of Dyspepsia. Am. Fam Physician. 1999;60:1774–1774. - PubMed
    1. Mahadeva S, Gok KL. Epidemiology of Functional Dyspepsia: a Global Perspective. 2006;12(17):2661–6. - PMC - PubMed
    1. Maes BD, Ghoos YF, Hiele MI, et al. Gastric Emptying Rate of Solids in Patients with Nonulcer Dyspepsia. Dig. Dis Sci. 1997;42:235–42. - PubMed
    1. Thumshirn M, Camilleri M, Saslow SB, et al. Gastric Accomodation in Non-Ulcer Dyspepsia and the Roles of Helicobacter Pylori Infection and Vagal Function. Gut. 1999;44:55–64. - PMC - PubMed
    1. Takashi T. Mechanisms of Interdigestive Migrating Motor Complex. J Neurogastroenterol Motil. 2012;18(3):246–257. - PMC - PubMed

LinkOut - more resources