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. 2013 Aug 27;5(8):452-7.
doi: 10.4254/wjh.v5.i8.452.

Alcohol and tobacco misuse: Reducing aerodigestive cancer risk

Affiliations

Alcohol and tobacco misuse: Reducing aerodigestive cancer risk

Gavin Wright et al. World J Hepatol. .

Abstract

Significant concerns over the health, social and economic burdens of the two most common, and frequently co-misused drugs of abuse, alcohol and tobacco, has encouraged focused but separate health promotion and disease prevention policies. However, this separation of focus means that while individuals who present with alcohol-related problems are increasingly supported to attain and maintain abstinence from alcohol they are not routinely assisted to refrain from smoking. This is tragically inopportune as alcohol and tobacco have an established "synergistic" effect on aerodigestive cancer risk. Moreover, even when patients successfully tackle their alcohol problems they remain at increased risk for developing these cancers, especially if they continue to smoke. A case series is presented together with a discussion on how service provision for co-misuse could be improved to obviate aerodigestive cancer risk. Given the prevalence of alcohol and tobacco use in the United Kingdom, these observations may have far reaching implications for the individual, health provider(s) and wider society.

Keywords: Aerodigestive cancer; Alcohol; Behavioural control; Co-dependence; Early intervention; Mortality; Preventive therapy; Substance misuse; Tobacco.

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References

    1. Klatsky AL, Armstrong MA. Alcohol, smoking, coffee, and cirrhosis. Am J Epidemiol. 1992;136:1248–1257. - PubMed
    1. Franceschi S, Talamini R, Barra S, Barón AE, Negri E, Bidoli E, Serraino D, La Vecchia C. Smoking and drinking in relation to cancers of the oral cavity, pharynx, larynx, and esophagus in northern Italy. Cancer Res. 1990;50:6502–6507. - PubMed
    1. Pelucchi C, Gallus S, Garavello W, Bosetti C, La Vecchia C. Cancer risk associated with alcohol and tobacco use: focus on upper aero-digestive tract and liver. Alcohol Res Health. 2006;29:193–198. - PMC - PubMed
    1. Talamini R, Bosetti C, La Vecchia C, Dal Maso L, Levi F, Bidoli E, Negri E, Pasche C, Vaccarella S, Barzan L, et al. Combined effect of tobacco and alcohol on laryngeal cancer risk: a case-control study. Cancer Causes Control. 2002;13:957–964. - PubMed
    1. Bosetti C, Gallus S, Peto R, Negri E, Talamini R, Tavani A, Franceschi S, La Vecchia C. Tobacco smoking, smoking cessation, and cumulative risk of upper aerodigestive tract cancers. Am J Epidemiol. 2008;167:468–473. - PubMed

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