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Practice Guideline
. 2014 Jan;93(1):13-32.
doi: 10.1007/s00277-013-1867-1. Epub 2013 Sep 12.

Treatment of invasive fungal infections in cancer patients-updated recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)

Sabine Mousset  1 , Dieter Buchheidt, Werner Heinz, Markus Ruhnke, Oliver A Cornely, Gerlinde Egerer, William Krüger, Hartmut Link, Silke Neumann, Helmut Ostermann, Jens Panse, Olaf Penack, Christina Rieger, Martin Schmidt-Hieber, Gerda Silling, Thomas Südhoff, Andrew J Ullmann, Hans-Heinrich Wolf, Georg Maschmeyer, Angelika Böhme
Affiliations
Practice Guideline

Treatment of invasive fungal infections in cancer patients-updated recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)

Sabine Mousset et al. Ann Hematol. 2014 Jan.

Abstract

The Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO) here presents its updated recommendations for the treatment of documented fungal infections. Invasive fungal infections are a main cause of morbidity and mortality in cancer patients undergoing intensive chemotherapy regimens. In recent years, new antifungal agents have been licensed, and agents already approved have been studied in new indications. The choice of the most appropriate antifungal treatment depends on the fungal species suspected or identified, the patient's risk factors (e.g., length and depth of neutropenia), and the expected side effects. This guideline reviews the clinical studies that served as a basis for the following recommendations. All recommendations including the levels of evidence are summarized in tables to give the reader rapid access to the information.

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